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Publications
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There are over 25 peer-reviewed journal publications validating the patented OrganOx technology for normothermic
organ preservation and repair prior to transplantation, and demonstrating its numerous benefits over conventional cold storage
and cold perfusion technologies: - Jamieson RW, Zilvetti M, Roy D, Hughes D, Morovat A, Coussios CC, Friend PJ. –
Transplantation (2011), in press. Hepatic steatosis and nortmothermic perfusion: preliminary experiments in a porcine model.
- T. Vogel, J.G. Brockmann, C.-C. Coussios and P.J. Friend - in “Methods
in Bioengineering”, edited by Martin Yarmush and Robert Langer, Elsevier Special Series on Biotechnology, in press.Normothermic
Machine Perfusion of the Liver.
- Vogel T, Brockmann JG
and Friend PJ – Current Opinions in Organ Transplantation (2010) 15 167-72 Ex-vivo normothermic liver perfusion :
an update.
- Brockmann J, Reddy S, Coussios C, Pigott D,
Guerriero D, Hughes D, Morovat A, Roy D, Winter L and Friend PJ – Annals of Surgery (2009) 250(1) 1-6.
Normothermic perfusion – a new paradigm for organ preservation.
- Reddy SP, Brockmann J and Friend PJ – Transplantation (2009) 87 631-2 Normothermic perfusion : a mini review.
- Jamieson RW and Friend PJ – Frontiers in Bioscience
(2008) 13 221-225. Organ reperfusion and preservation.
- Jamieson
RW and Friend PJ – Transplantation Reviews (2006) 20 172-178. Normothermic organ preservation.
- Reddy S and Friend PJ – Current Opinions in Organ Transplantation
(2005) 10 95-100. Liver transplantation outcomes using donors after cardiac death.
- Reddy S, Greenwood J, Maniakin N, Bhattacharjya S, Zivetti M, Brockmann J, James T, Piggott
D and Friend PJ – Liver Transplantation (2005) 11 35-38. Non-heart-beating donor porcine livers:
the adverse effect of cooling.
- Rees MA, Butler AJ, Brons
GM, Negus MC, Skepper JN and Friend PJ – Xenotransplantation (2005) 12 13-19. Evidence of macrophage
receptors capable of direct recognition of xenogeneic epitopes without opsonization.
- Rees MA, Butler AJ, Negus MC, Davies HSF and Friend PJ – Transplantation (2004) 77
1416-1423. Classical pathway complement destruction is not responsible for the loss of human erythrocytes during
porcine liver perfusion.
- Reddy SP, Bhattacharjya S,
Maniakin N, Greenwood J, Guerreiro D, Hughes D, Imber CJ, Piggott DW, Fuggle S, Taylor R and Friend PJ – Transplantation
(2004) 77 1328-1332. Preservation of porcine non-heart-beating donor livers by sequential cold storage and
warm perfusion.
- Reddy S, Zivetti M, Brockmann J, McClaren
A and Friend PJ – Liver Transplantation (2004) 10 1223-1232. Liver transplantation from non-heart beating
donors: Current status and future prospects.
- McLaren
AJ and Friend PJ – Transplantation International (2003) 16 701-708. Trends in organ preservation.
- St. Peter SD, Imber CJ, Kay J, James T and Friend PJ – Transplantation
Proceedings (2003) 35 1587-1590. Hepatic control of perfusate homeostasis during normothermic
extracoropreal preservation.
- Imber CJ, St Peter SD, Handa
A and Friend PJ – Liver Transplantation (2002) 8 415-423.
- St. Peter SD, Imber CJ and Friend PJ – Lancet (2002) 359 604-613. Liver and kidney preservation
by perfusion.
- Imber CJ, St. Peter SD, Lopez I, Lemonde
H, Rees M, Butler A, Clayton PT and Friend PJ – American Journal of Transplantation (2002) 2 593-599. Optimisation
of bile production during normothermic preservation of porcine livers.
- Rees Ma, Butler AJ, Davies HSF, Bolton E, Wight DGD, Skepper J, White DJG and Friend PJ – Transplantation
(2002) 73 1460-1467. Porcine livers perfused with human blood mount a graft-versus-host reaction.
- Rees MA, Butler AJ, Chavaz-Cartaya G, Wight DGD, Casey ND, Alexander
G, Khuder SA, White DJG and Friend PJ – Transplantation (2002) 73 1194-2002. Prolonged
function of extracorporeal hDAF transgenic pig livers perfused with human blood.
- Butler AJ, Rees MA, Wight DGD, Casey ND, Alexander G, White DJG and Friend PJ – Transplantation (2002)
73 1212-1218. Successful extracorporeal porcine liver perfusion for 72 hours.
- St. Peter SD, Imber CJ, Lopez I, Hughes D and Friend PJ – British Journal of Surgery
(2002) 89 609-616. Extended preservation of non-heart beating donor livers with normothermic machine perfusion.
- Imber CJ, St Peter SD, Lopez I, Pigott D, James T, Taylor R, McGuire
J, Hughes D, Butler A, Rees M and Friend PJ – Transplantation (2002) 73 701-709. Advantages of normothermic
perfusion over cold storage in liver preservation.
- St Peter
SD, Imber CJ, Lopez I, McGuire J, James T, Taylor R and Friend PJ – Liver Transplantation
(2002) 8 21-26. β-galactosidase as a marker of ischaemic injury and a mechanism for viability assessment
in porcine liver transplantation.
- Imber CJ, St Peter SD, Lopez
I, Guiver L and Friend PJ – Liver transplantation (2002) 8 545-549. Current practice regarding the
use of fatty livers: A transatlantic survey.
- St Peter
SD, Imber CJ, Lopez I, McGuire J, James T, Taylor R, D Pigott and Friend PJ – Transplantation proceedings
(2001) 33 3753-3755. β-galactosidase as a novel marker of ischaemic injury and a mechanism for viability assessment
in liver transplantation.
- Friend PJ, Imber CJ, St. Peter
SD, Lopez I, Butler AJ and Rees MA – Transplantation Proceedings (2001) 33 3436-3438. Normothermic
perfusion of the isolated liver.
- Imber CJ, St Peter SD, Lopez
I, and Friend PJ – Transplantation Proceedings (2001) 33 3718-3719. Use of laser Doppler as a non-invasive
measure of ischaemia reperfusion injury in the pig liver.
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OrganOx Ltd is a company registered in England with number 06557113, VAT number
943672795 Registered office address: 9400 Garsington Road, Oxford
Business Park, Oxford OX4 2HN, UK
Copyright
OrganOx Ltd. 2011
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