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Dr Les Russell
Les has been the CEO of OrganOx since the company was formed in April 2008. He handed over this role to Craig Marshall in January 2017, and has taken up the position of company Chairman. Les holds first class honours and PhD degrees in Chemistry from the University of London and has more than 25 years experience in the medical devices industry.
Prior to joining OrganOx, Les was Managing Director of Chromogenex plc, an AIM listed company developing and manufacturing light devices for non-ablative surgical and cosmetic use. In his 2 years as Managing Director, sales were increased from £2.4m to £4.5m and a loss of £150K reversed into a profit of £376K.
Until 2000, Les was Director of Marketing and Business Strategy for the Biotech Division of Baxter Export Corporation with responsibility for a product portfolio of $60m spanning medical devices and biopharmaceuticals.
Earlier in his career, he worked with Ilford Limited, Ciba-Corning Diagnostics and Cambridge Life Sciences plc. At Cambridge Life Sciences he had the role of Business Development Director with board responsibility for R&D and business development activities where he was instrumental in the sale of the company to Medirace (Medeva) and then to Byk-Gulden and also in the acquisition of Walker Laboratories.
CHIEF EXECUTIVE OFFICER
Craig joined OrganOx in December 2016, and took over the role of CEO from Dr Les Russell in January 2017.
Prior to joining OrganOx, Craig was Managing Director from 2010 of the award winning business Siemens Magnet Technology. During the period 2010-2016, he was also an executive member of the Siemens Healthcare MRI business, the undisputed market leader. During his time in these roles, Siemens Magnet Technology developed a revolutionary new magnet contained with the World's strongest clinical MRI system, the Siemens MRI 7 Tesla product, MAGNETOM Terra.
Craig is a fellow of the Institution of Mechanical Engineers, he holds a first degree from the University of Liverpool, and an MBA with Distinction from the acclaimed University of Warwick Business School.
Earlier in his career he worked at Oxford Instruments, Amersham Plc and GE Healthcare in a variety of management and leadership roles, within the in vivo diagnostics sector.
Professor Peter Friend
CHIEF MEDICAL OFFICER
Peter is one of two academic founders of OrganOx and has been its medical director since April 2008, being primarily responsible for the pre-clinical and clinical trials of OrganOx's patented normothermic organ perfusion technology.
Peter is Professor of Transplantation at the University of Oxford and Director of the Oxford Transplant Centre, where he is responsible for the kidney, small bowel and pancreatic transplant programmes. He is also a Past President of the British Transplantation Society. Earlier in his career, Peter was Clinical Director of the Transplant Centre at Addenbrooke’s Hospital, Cambridge, one of the UK’s leading liver transplant centres and previously, visiting Assistant Professor of Surgery at Indiana University Medical Centre, USA where he established their liver transplant programme.
Peter's research interests lie primarily in novel applications of normothermic organ perfusion, ranging from its use for extracorporeal support to preservation and repair prior to transplantation. He has published over 25 papers on the topic of normothermic perfusion, the basis of the OrganOx technology, as well as in the areas of clinical transplantation, immunosuppression, monoclonal antibodies, xenotransplantation, liver perfusion and aspects of general surgery.
Professor Constantin Coussios
CHIEF TECHNICAL OFFICER
Constantin is the second academic founder of OrganOx, and has been working with Peter for more than 20 years on the development of normothermic organ perfusion technology. He has been OrganOx's technical director since April 2008 and leads the company's research and development activities, being primarily responsible for the device development programme with Team Consulting Limited. He has extensive expertise in general engineering, instrumentation, control, haemodynamics and drug delivery.
Constantin holds BA, MEng, MA and PhD degrees in engineering from the University of Cambridge, following which he held post-doctoral research positions at the University of Cincinnati and at Boston University. He was then appointed to the first lectureship in Biomedical Engineering at the University of Oxford in 2004 and to the first statutory professorship in biomedical engineering at the University in 2011, jointly with a professorial fellowship at Magdalen College. He currently heads the Biomedical Ultrasonics and Biotherapy Laboratory within the Oxford Institute of Biomedical Engineering, a research group of some 35 researchers that has attracted over £20m of research funding to work on novel ultrasound-based therapies for non-invasive surgery and drug delivery. He has more than 100 publications in the general area of biomedical engineering, is the author of 17 patents, and has gained several awards and prizes, including the Institute of Acoustics young person's award for innovation in acoustical engineering, and a challenging engineering award from the UK's Engineering and Physical Sciences Research Council. He was elected as the youngest Fellow of the Acoustical Society of America in 2009, as the Society's recipient of the Bruce Lindsay award in 2011, and as the recipient of the Fred Lizzi award of the International Society for Therapeutic Ultrasound in 2012.
Dr Toni Day
DIRECTOR OF QUALITY AND REGULATORY AFFAIRS
Toni joined OrganOx in April 2011. Toni holds a BSc Honours degree in Biochemistry and a DPhil in Neuropharmacology from Oxford University.
Previously Toni has worked for a number of startup companies in the medical device, in vitro diagnostics and pharmaceutical arenas.
Most recently, Toni served 7 years at Oxford Immunotec Ltd, starting as a Senior Scientist working alongside the CEO and then through promotion to Director of Product Development, with line managementresponsibilities for 12 scientists and senior scientists. Toni has 11 years experience in product development and regulatory submissions for both European and US approval.
Daniel has a BEng in Engineering Systems and over twenty years experience in research engineering, including the role of senior research engineer at the Marconi Research Centre (now BAE Systems Advanced Technology Centre). His specialist area of interest at Marconi was high temperature super conducting microwave circuits. Daniel also worked at University College London as senior research engineer and laboratory manager, where he designed and built specialist human movement and balance investigational equipment. During his career he has received numerous industry awards for his innovation and technology. Daniel joined OrganOx in 2014.
Having Completed his degree in Biological Sciences at the University of Birmingham, Andy worked for 9 years at the CRO BioFocus (now part of Charles River Laboratories International Inc.), in various scientific, project management and business development roles. Andy then spent 5 years at Isis Innovation, the technology transfer company for the University of Oxford, managing the commercialisation of intellectual property developed at the University. Andy joined OrganOx in February 2014.
FINANCE AND HR DIRECTOR
Alex has been the Finance Director of OrganOx since October 2016. He is a Chartered Accountant (ICAEW) with over 20 years post qualification experience in various sectors, including medical diagnostics, technology, telecoms and manufacturing. He holds a degree in Economics (University of East Anglia), and MSc in Economics (Birkbeck, London). Prior to joining OrganOx, Alex was CFO of Adestra Group, an email marketing company where he was part of the main board and instrumental in the turnaround of the company. This included rapid international growth, expanding into the US and Asia, obtaining VC funding from 2008-2016, increasing turnover from £2 - £8 million, and turning a loss into a £1 million profit. During this time Alex was also responsible for HR, managing a team of up to 125 employees.
Earlier in his career, he gained experience working with several Blue-chip companies, including Amersham, Cable & Wireless, General Electric, Verizon and Vodafone.
Chris holds BSc Honours degrees in both Biomedical Sciences and Perfusion Science. Having gained accreditation from Kings College Hospital in 2006 as a Clinical Perfusion Scientist, Chris spent the following 8 years specialising in liver perfusion and cardiothoracic perfusion for the NHS and private sector. Chris joined OrganOx in 2014.
Lucy has more than ten years experience in liver transplantation and organ donation from Addenbrooke's Hospital, Cambridge. Her experience comes from working as an anaesthetic practitioner, leading the transplant theatre teams, and working as part of the organ retrieval team. For the past 6 years Lucy's experience is from her role as Clinical Research Associate in the University of Cambridge Department of Surgery. Her areas of research interest have focussed on novel technologies for improving donor organ function, including Normothermic Regional Perfusion, and ex vivo liver preservation. She was awarded the 2016 Calne-Williams Medal at the British Transplantation Society Annual Congress for her work on liver steatosis. Lucy joined OrganOx in April 2016.