Evidence-based improvements in liver transplantation outcomes
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A back-to-base experience of human normothermic ex situ liver perfusion: does the chill kill?
Bral M, Dajani K, Leon Izquierdo D et al. Liver Transpl. 2019;25:848–58.
A nonrandomised pilot study assessing whether the OrganOx metra can be used with a back-to-base model without impacting patient outcomes.
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Liver transplantation with a normothermic machine preserved fatty nonagenarian liver: A case report
Manzia TM, Toti L, Quaranta C, et al. Int J Surg Rep. 2019;57:163–6.
This case report details how functional assessment of a nonagenarian liver with the OrganOx metra resulted in successful transplantation.
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Liver transplantation from non-heart beating donors: Current status and future prospects.
Reddy S, Zivetti M, Brockmann J, McClaren A and Friend PJ – Liver Transplantation (2019) 10 1223-1232.
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A randomized trial of normothermic preservation in liver transplantation
Nasralla D, Coussios CC, Mergental H, et al. Consortium for Organ Preservation in Europe. Nature. 2018;557(7703):50–56.
The first randomised controlled trial comparing machine perfusion technology with static cold storage in human liver transplantation. In this trial, the OrganOx metra was transported to and from the donor centre to minimise cold storage time.
Compared with static cold storage, the OrganOx metra achieved a 50% lower level of graft injury despite a 50% lower rate of organ discard and a 54% longer mean preservation time.
Want to know more about the metra?
If you would like to know more about the metra and how it could benefit your liver transplantation unit, click ‘Contact Us’ and a member of the OrganOx team will be in touch.
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