Up to 24 hour^† donor liver preservation with OrganOx metra supports liver transplantation in people requiring complex and/or lengthy surgeries^1–5

People on the liver transplant waiting list with complex conditions can be at a disadvantage due to concerns over prolonged cold ischaemia time using static cold storage.⁵ The OrganOx metra can help overcome these limitations of static cold storage by providing up to 24 hours^† of preservation without compromising outcomes.^1–4 These extra hours may allow more time for preoperative preparation of all liver transplant recipients, potentially reducing the risk of complications following surgery.^2,4,6,7

Up to 24 hour^† organ preservation with the metra helps address patient travel challenges and support liver allocation logistics^2–4,8

Long patient travel times to transplant centres is associated with increased mortality and a reduced likelihood of transplantation⁸. OrganOx metra extends the transplantation window for these patients by overcoming the 12-hour^† preservation limitations of conventional static cold storage.^2–4,9

References: ^1. She WH et al. World J Hepatol 2018;10:308–318. ^2. Nasralla D et al. Nature 2018;557(7703):50–56. ^3. Mergental H et al. Hepatology 2018; 68(1):(Suppl). ^4. Bral M et al. Liver Transpl. 2019; 25(6):848–858. ^5. Vining CC et al. Liver Transpl. 2017;23:S27–S33. ^6. Wiklund RA. Crit Care Med 2004;32(4Suppl):S106–115. 7. Abbas N et al. Health Serv Insights 2017;10:1178632917691270. ^8. Webb GJ et al. Am J Transplant 2019;19(1):208–220. ^9. De Vries R et al. Transplantation 2018;102:S396.

^† Disclaimer: metra® is FDA-approved for normothermic liver perfusion in the United States and can preserve the donor organ in a functional state for up to 12 hours.

UK/US MD-040-12-1 - September 2022